- *Season Finale* – 30 Rock – NBC @ 9/8c
- *Season Finale* – October Road – ABC @ 10/9c
- *Season Finale* – This American Life – Showtime @ 10:30/9:30c
- *New* – Adventures in Hollyhood – MTV @ 10/9c
- *New* – Are You Smarter Than a 5th Grader? – FOX @ 8/7c
- *New* – CSI – CBS @ 9/8c
- *New* – ER – NBC @ 10/9c
- *New* – Grey’s Anatomy – ABC @ 9/8c
- *New* – Human Giant – MTV @ 10:30/9:30c
- *New* – My Name is Earl – NBC @ 8/7c
- *New* – Nick Cannon Presents: Short Circuitz – MTV @ 9:30/8:30c
- *New* – Penn & Teller: Bullshit – Immigration – Showtime @ 10/9c
- *New* – Pimp My Ride – MTV @ 9/8c
- *New* – Scrubs – NBC @ 9:30/8:30c
- *New* – Shark – CBS @ 10/9c
- *New* – Smallville – CW @ 8/7c
- *New* – Supernatural – CW @ 9/8c
- *New* – Survivor – CBS @ 8/7c
- *New* – The Office – NBC @ 8:30/7:30c
- *New* – The Showbiz Show with David Spade – Comedy Central @ 10:30/9:30c
- *New* – Trading Spouses – FOX @ 9/8c
- *New* – Ugly Betty – ABC @ 8/7c
