- Dirt – FX @ 10/9c
- I Can Make You Thin with Paul McKenna – TLC @ 9/8c
- Rock of Love with Bret Michaels – VH1 @ 9/8c (90-Minute Season Finale)
- Viva Hollywood! – VH1 @ 10:30/9:30c (90-Minute Series Premiere)
- Comedy Central Special: Night of Too Many Stars: An Overbooked Benefit for Autism Education – Comedy Central @ 8/7c (2-Hour Special)
- John Adams – HBO @ 9/8c (Part 6 of 7)
- America’s Funniest Home Video – ABC @ 7/6c
- Big Brother – CBS @ 8/7c
- Celebrity Fit Club – VH1 @ 8/7c
- Cold Case – CBS @ 9/8c
- Desperate Housewives – ABC @ 9/8c
- Dexter – CBS @ 10/9c (New to CBS)
- Eli Stone – ABC @ 10:02/9:02c
- Everybody Hates Chris – CW @ 8/7c
- Keeping Up With the Kardashians – E! @ 10/9c
- King of the Hill – FOX @ 8:30/7:30c
- Oprah’s Big Give – ABC @ 8/7c (New Time Slot)
- The Game – CW @ 9/8c
- The Simpsons – FOX @ 8/7c
- The Tudors – Showtime @ 9/8c
- Tracey Ullman’s State of the Union – Showtime @ 10/9c
- *New* – America’s Funniest Home Video @ 7/6c
- *New* – Oprah’s Big Give @ 8/7c (New Time Slot)
- *New* – Desperate Housewives @ 9/8c
- *New* – Eli Stone @ 10:02/9:02c
- *New* – Big Brother @ 8/7c
- *New* – Cold Case @ 9/8c
- *New* – Dexter @ 10/9c (New to CBS)
- *New* – Everybody Hates Chris @ 8/7c
- *New* – The Game @ 9/8c
- *New* – The Simpsons @ 8/7c
- *New* – King of the Hill @ 8:30/7:30c
- *Special* – Comedy Central Special: Night of Too Many Stars: An Overbooked Benefit for Autism Education @ 8/7c (2-Hour Special)
- *New* – Keeping Up With the Kardashians @ 10/9c
- *Season Finale* – Dirt @ 10/9c
- *Special* – John Adams @ 9/8c (Part 6 of 7)
- *New* – The Tudors @ 9/8c
- *New* – Tracey Ullman’s State of the Union @ 10/9c
- *Season Finale* – I Can Make You Thin with Paul McKenna @ 9/8c
- *New* – Celebrity Fit Club @ 8/7c
- *Season Finale* – Rock of Love with Bret Michaels @ 9/8c (90-Minute Season Finale)
- *Series Premiere* – Viva Hollywood! @ 10:30/9:30c (90-Minute Series Premiere)
- *New* – America’s Funniest Home Video – ABC
- *New* – Big Brother – CBS
- *New* – Celebrity Fit Club – VH1
- *New* – Everybody Hates Chris – CW
- *Special* – Night of Too Many Stars: An Overbooked Benefit for Autism Education – Comedy Central (2-Hour Special)
- *New* – Oprah’s Big Give – ABC (New Time Slot)
- *New* – The Simpsons – FOX
- *New* – King of the Hill – FOX
- *New* – Cold Case – CBS
- *New* – Desperate Housewives – ABC
- *Season Finale* – I Can Make You Thin with Paul McKenna – TLC
- *Special* – John Adams – HBO (Part 6 of 7)
- *Season Finale* – Rock of Love with Bret Michaels – VH1 (90-Minute Season Finale)
- *New* – The Game – CW
- *New* – The Tudors – Showtime
- *New* – Dexter – CBS (New to CBS)
- *Season Finale* – Dirt – FX
- *New* – Eli Stone – ABC (10:02/9:02c)
- *New* – Keeping Up With the Kardashians – E!
- *New* – Tracey Ullman’s State of the Union – Showtime
- *Series Premiere* – Viva Hollywood! – VH1 (90-Minute Series Premiere)