Season Finale
- Rookie Blue (#112/113) – ABC @ 9/8c & 10/9c (2 New Episodes Including Season Finale)
Series Premiere
- Beast Legends (#101) – Syfy @ 10/9c
- Nikita (#101) – CW @ 9/8c
Season Premiere
- Destination Truth (#401) – Syfy @ 9/8c
- The Vampire Diaries (#201) – CW @ 8/7c
- Watch What Happens: Live (#301) – Bravo @ 10/9c
Specials/Sports
- NFL Kickoff 2010 – NBC @ 7:30/6:30c (1-Hour Special)
- Sunday Night Football: Minnesota Vikings at New Orleans Saints – NBC @ 8:30/7:30c
New
- Ace of Cakes – Food Network @ 10/9c
- Big Brother (#1228) – CBS @ 8/7c
- Come Dine with Me (#110) – BBC America @ 10/9c
- Extreme Cuisine with Jeff Corwin – Food Network @ 8/7c
- Family Style – Food Network @ 10:30/9:30c
- Jersey Shore (#207-60) – MTV @ 10/9c
- Jimmy Kimmel Live – ABC @ 1:36AM/12:36AMc
- Late Night with Jimmy Fallon – NBC @ 12:37AM/11:37PMc
- Late Show with David Letterman – CBS @ 11:35/10:35c
- On the Road with Austin & Santino (#107) – Lifetime @ 10:30/9:30c
- Project Runway (#807-90) – Lifetime @ 9/8c (90-Minute New Episode)
- The Late Late Show with Craig Ferguson – CBS @ 1:37AM/12:37PMc
- The Real Housewives of DC (#105) – Bravo @ 9/8c
- The Squad: Prison Police – A&E @ 10/9c
- The Tonight Show with Jay Leno – NBC @ 11:35/10:35c
ABC
- *Season Finale* – Rookie Blue (#112/113) @ 9/8c & 10/9c (2 New Episodes Including Season Finale)
- *New* – Jimmy Kimmel Live @ 1:36AM/12:36AMc
CBS
- *New* – Big Brother (#1228) @ 8/7c
- *New* – Late Show with David Letterman @ 11:35/10:35c
- *New* – The Late Late Show with Craig Ferguson @ 1:37AM/12:37PMc
CW
- *Season Premiere* – The Vampire Diaries (#201) @ 8/7c
- *Series Premiere* – Nikita (#101) @ 9/8c
NBC
- *Sports* – NFL Kickoff 2010 @ 7:30/6:30c (1-Hour Special)
- *Sports* – Sunday Night Football: Minnesota Vikings at New Orleans Saints @ 8:30/7:30c
- *New* – The Tonight Show with Jay Leno @ 11:35/10:35c
- *New* – Late Night with Jimmy Fallon @ 12:37AM/11:37PMc
A&E
- *New* – The Squad: Prison Police @ 10/9c
BBC America
- *New* – Come Dine with Me (#110) @ 10/9c
Bravo
- *New* – The Real Housewives of DC (#105) @ 9/8c
- *Season Premiere* – Watch What Happens: Live (#301) @ 10/9c
Food Network
- *New* – Extreme Cuisine with Jeff Corwin @ 8/7c
- *New* – Ace of Cakes @ 10/9c
- *New* – Family Style @ 10:30/9:30c
Lifetime
- *New* – Project Runway (#807-90) @ 9/8c (90-Minute New Episode)
- *New* – On the Road with Austin & Santino (#107) @ 10:30/9:30c
MTV
- *New* – Jersey Shore (#207-60) @ 10/9c
Syfy
- *Season Premiere* – Destination Truth (#401) @ 9/8c
- *Series Premiere* – Beast Legends (#101) @ 10/9c
7:30/6:30c
- *Sports* – NFL Kickoff 2010 – NBC (1-Hour Special)
8:00/7:00c
- *New* – Big Brother (#1228) – CBS
- *New* – Extreme Cuisine with Jeff Corwin – Food Network
- *Season Premiere* – The Vampire Diaries (#201) – CW
8:30/7:30c
- *Sports* – Sunday Night Football: Minnesota Vikings at New Orleans Saints – NBC
9:00/8:00c
- *Season Premiere* – Destination Truth (#401) – Syfy
- *Series Premiere* – Nikita (#101) – CW
- *New* – Project Runway (#807-90) – Lifetime (90-Minute New Episode)
- *Season Finale* – Rookie Blue (#112/113) – ABC (2 New Episodes Including Season Finale)
- *New* – The Real Housewives of DC (#105) – Bravo
10:00/9:00c
- *New* – Ace of Cakes – Food Network
- *Series Premiere* – Beast Legends (#101) – Syfy
- *New* – Come Dine with Me (#110) – BBC America
- *New* – Jersey Shore (#207-60) – MTV
- *Season Finale* – Rookie Blue (#112/113) – ABC (2 New Episodes Including Season Finale)
- *New* – The Squad: Prison Police – A&E
- *Season Premiere* – Watch What Happens: Live (#301) – Bravo
10:30/9:30c
- *New* – Family Style – Food Network
- *New* – On the Road with Austin & Santino (#107) – Lifetime
11:30/10:30c
- *New* – Late Show with David Letterman – CBS (11:35/10:35c)
- *New* – The Tonight Show with Jay Leno – NBC (11:35/10:35c)
12:30AM/11:30PMc
- *New* – Late Night with Jimmy Fallon – NBC (12:37AM/11:37PMc)
1:30AM/12:30AMc
- *New* – Jimmy Kimmel Live – ABC (1:36AM/12:36AMc)
- *New* – The Late Late Show with Craig Ferguson – CBS (1:37AM/12:37PMc)
